CCNE1, cyclin E1, 898

N. diseases: 133; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 Biomarker disease RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522 2007
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer
0.240 Biomarker disease RGD Overexpression of p21, cyclin E and decreased expression of p27 in DMBA (7, 12-dimethylbenzanthracene)-induced rat ovarian carcinogenesis. 12713563 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.220 Biomarker group RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522 2007
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.220 Biomarker disease RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522 2007
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
0.200 Biomarker group RGD Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis. 14614307 2000
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.200 Biomarker disease RGD Growth pattern switch of renal cells and expression of cell cycle related proteins at the early stage of diabetic nephropathy. 17825795 2007
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.200 Biomarker group RGD Different cell cycle regulation of vascular smooth muscle in genetic hypertension. 12847112 2003
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker phenotype RGD Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors. 12602925 2003
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker phenotype RGD Effect of energy restriction on cell cycle machinery in 1-methyl-1-nitrosourea-induced mammary carcinomas in rats. 12649181 2003
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury
0.200 Biomarker disease RGD Impaired hepatic regeneration by ischemic preconditioning in a rat model of small-for-size liver transplantation. 17584601 2007
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma
0.200 Biomarker disease RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522 2007
Hepatoblastoma Caused By Somatic Mutation
0.200 Biomarker disease RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 Biomarker disease LHGDN Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis. 12601350 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 AlteredExpression group LHGDN HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells. 16912169 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 AlteredExpression group LHGDN Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2. 15665273 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 AlteredExpression group LHGDN The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node. 12096344 2002
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 AlteredExpression group LHGDN Cyclin E expression in breast cancer correlates with negative steroid receptor status, HER2 expression, tumor grade and proliferation. 16761619 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 Biomarker group LHGDN Which cyclin E prevails as prognostic marker for breast cancer? Results from a retrospective study involving 635 lymph node-negative breast cancer patients. 16740753 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 Biomarker group LHGDN Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells. 12444551 2002
CUI: C0017638
Disease: Glioma
Glioma
0.050 AlteredExpression disease LHGDN Expression of cyclin D1, D3, E, and p27 in human renal cell carcinoma analysed by tissue microarray. 12778072 2003
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.040 Biomarker group LHGDN Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas. 17360482 2007
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.020 AlteredExpression disease LHGDN Protein levels of p21, p27, cyclin E and Bax predict sensitivity to cisplatin and paclitaxel in head and neck squamous cell carcinomas. 14719078 2004
CUI: C0023418
Disease: leukemia
leukemia
0.020 Biomarker disease LHGDN [The significance of cyclin E expression and cyclin E-dependent kinase inhibitor in adult acute leukemia]. 12133429 2002
CUI: C0023418
Disease: leukemia
leukemia
0.020 AlteredExpression disease LHGDN Cyclin E but not bcl-2, bax or mcl-1 is differentially expressed in ZAP 70-positive and ZAP 70-negative B-CLL cells. 16538501 2006
CUI: C0016059
Disease: Fibrosis
Fibrosis
0.010 Biomarker phenotype LHGDN Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis. 12601350 2003